G12C INHIBITOR 12
K-Ras(G12C) inhibitor 12
CAS: 1469337-95-8
Molecular Formula: C15H17ClIN3O3
G12C INHIBITOR 12 - Names and Identifiers
G12C INHIBITOR 12 - Physico-chemical Properties
| Molecular Formula | C15H17ClIN3O3 |
| Molar Mass | 449.67 |
| Density | 1.736±0.06 g/cm3(Predicted) |
| Boling Point | 680.2±55.0 °C(Predicted) |
| Solubility | DMSO: ≥ 48 mg/mL |
| pKa | 8.60±0.50(Predicted) |
| Storage Condition | -20℃ |
| In vitro study | K-Ras(G12C) inhibitor 12 belongs to a series of small molecules that irreversibly bind to a common tumorigenic mutant K-Ras(G12C) and block the K-Ras(G12C) interaction. Some of them decreased activity and increased apoptosis of G12C-containing cancer cell lines. K-Ras(G12C) inhibitor 12 belongs to a family of small molecules that irreversibly bind to a common tumorigenic mutant K-Ras(G12C) and block K-Ras(G12C) interactions. Some of them decreased activity and increased apoptosis of G12C-containing cancer cell lines. |
G12C INHIBITOR 12 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.224 ml | 11.119 ml | 22.238 ml |
| 5 mM | 0.445 ml | 2.224 ml | 4.448 ml |
| 10 mM | 0.222 ml | 1.112 ml | 2.224 ml |
| 5 mM | 0.044 ml | 0.222 ml | 0.445 ml |
Last Update：2024-01-02 23:10:35
G12C INHIBITOR 12 - Reference Information
| biological activity | K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of carcinogenic K-Ras(G12C). K-Ras(G12C) inhibitor 12 is an allosteric inhibitor of carcinogenic K-Ras(G12C). |
| in vitro study | K-Ras(G12C) inhibitor 12 is a series of small molecules that irreversibly bind to a common tumorigenic mutant K-Ras(G12C) and block K-Ras(G12C) interaction. Some of them decreased activity and increased apoptosis of G12C-containing cancer cell lines. K-Ras(G12C) inhibitor 12 belongs to a series of small molecules, which irreversibly bind to a common tumorigenic mutant K-Ras(G12C) and block K-Ras(G12C) interaction. Some of them decreased activity and increased apoptosis of G12C-containing cancer cell lines. |
| target | TargetValue K-Ras(G12C) () |
| Target | Value |
Last Update：2024-04-09 21:54:55
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Spot supply
Product Name: K-Ras(G12C) inhibitor 12 Visit Supplier Webpage Request for quotationCAS: 1469337-95-8
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Spot supply
Product Name: K-Ras(G12C) inhibitor 12 Visit Supplier Webpage Request for quotationCAS: 1469337-95-8
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: K-Ras(G12C) inhibitor 12 Visit Supplier Webpage Request for quotationCAS: 1469337-95-8
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: K-Ras(G12C) inhibitor 12 Visit Supplier Webpage Request for quotationCAS: 1469337-95-8
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
View History
G12C INHIBITOR 12
METHYLENCYCLOPENTANE
TOSLAB 300105
Phosphonic acid,methyl-, monomethyl ester, vanadium(3+) salt (8CI)
BENZOTHIAZOLIUM, 2-[[5-(AMINOCARBONYL)-3-[(3-ETHYL-2(3H)-BENZOTHIAZOLYLIDENE)METHYL]-2-CYCLOHEXEN-1-YLIDENE]METHYL]-3-ETHYL-, IODIDE
ETIOPORPHYRIN I-DIHYDROBROMID
METHYL 3-(4-HYDROXYPHENYL)PROPIONATE 3-(4-羟苯基)丙酸甲酯
Methyl 2-bromobenzo[d]thiazole-6-carboxylate
α-Conotoxin AuIB
N-Dodecyl-B-iminodipropionic acid disodium salt
METHYLENCYCLOPENTANE
TOSLAB 300105
Phosphonic acid,methyl-, monomethyl ester, vanadium(3+) salt (8CI)
BENZOTHIAZOLIUM, 2-[[5-(AMINOCARBONYL)-3-[(3-ETHYL-2(3H)-BENZOTHIAZOLYLIDENE)METHYL]-2-CYCLOHEXEN-1-YLIDENE]METHYL]-3-ETHYL-, IODIDE
ETIOPORPHYRIN I-DIHYDROBROMID
METHYL 3-(4-HYDROXYPHENYL)PROPIONATE 3-(4-羟苯基)丙酸甲酯
Methyl 2-bromobenzo[d]thiazole-6-carboxylate
α-Conotoxin AuIB
N-Dodecyl-B-iminodipropionic acid disodium salt